Wound bed preparation with NPWT in diabetic foot ulcers: case report

Background Negative Pressure Wound Therapy (NPWT) is primarily used for very complex chronic wounds. The surgical treatment of the diabetic wounds with loss of soft tissue usually consists of closure using split-thickness skin grafts or transposition flaps. However, the first step consists of standard wound care with moist gauze dressing with the aim to prepare the wound bed for final closure. Clinical and experimental studies reported that negative pressure increases local blood flow and decreases bacterial colonization. Localized negative pressure removes fluids from the wound and promotes the granulation tissue, which is required for wound closure.